Spectra for:
Santos Fustero, María Sánchez-Roselló, Vanessa Rodrigo, Carlos del Pozo, Juan F. Sanz-Cervera, Antonio Simón
Compound (+)-#12 KMANUEVHEGKSMG-LBPRGKRZSA-N
Compound 1 (+/-)-BENZYL-1-AMINO-6,6-DIFLUORO-3-CYCLOHEXENE-1-CARBOXYLATE
Compound 3B (-)-N-[(1S)-1-PHENYLETHYL]-1-CHLORO-2,2-DIFLUORO-4-PENTENIMIDOYL-CHLORIDE
![(-)-N-[(1S)-1-PHENYLETHYL]-1-CHLORO-2,2-DIFLUORO-4-PENTENIMIDOYL-CHLORIDE](/api/compound/IJW0JQwvxUa.png?h=300&w=458 "(-)-N-[(1S)-1-PHENYLETHYL]-1-CHLORO-2,2-DIFLUORO-4-PENTENIMIDOYL-CHLORIDE")
Compound 3C (-)-N-[(1R)-2-METHOXY-1-PHENYLETHYL]-1-CHLORO-2,2-DIFLUORO-4-PENTENIMIDOYL-CHLORIDE
![(-)-N-[(1R)-2-METHOXY-1-PHENYLETHYL]-1-CHLORO-2,2-DIFLUORO-4-PENTENIMIDOYL-CHLORIDE](/api/compound/JVGm18YMAS9.png?h=300&w=458 "(-)-N-[(1R)-2-METHOXY-1-PHENYLETHYL]-1-CHLORO-2,2-DIFLUORO-4-PENTENIMIDOYL-CHLORIDE")
Compound 5 F (-)-2-(TRIMETHYLSILYL)-ETHYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-IMINO]-5-HEXENOATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-IMINO]-5-HEXENOATE](/api/compound/Ud8dvVN3kt.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-IMINO]-5-HEXENOATE")
Compound 5A ETHYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE
![ETHYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE](/api/compound/8DRHcriDwUH.png?h=300&w=458 "ETHYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE")
Compound 5B BENZYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE
![BENZYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE](/api/compound/DTDxdxAn9iq.png?h=300&w=458 "BENZYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE")
Compound 5C 2-(TRIMETHYLSILYL)-ETHYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE
![2-(TRIMETHYLSILYL)-ETHYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE](/api/compound/6KoGJabIZcQ.png?h=300&w=458 "2-(TRIMETHYLSILYL)-ETHYL-3,3-DIFLUORO-2-[(4-METHOXYPHENYL)-IMINO]-5-HEXENOATE")
Compound 5D (-)-BENZYL-3,3-DIFLUORO-2-[[(1S)-1-PHENYLETHYL]-IMINO]-5-HEXENOATE
![(-)-BENZYL-3,3-DIFLUORO-2-[[(1S)-1-PHENYLETHYL]-IMINO]-5-HEXENOATE](/api/compound/HbC5JuTdBdB.png?h=300&w=458 "(-)-BENZYL-3,3-DIFLUORO-2-[[(1S)-1-PHENYLETHYL]-IMINO]-5-HEXENOATE")
Compound 5E (-)-BENZYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-IMINO]-5-HEXENOATE
![(-)-BENZYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-IMINO]-5-HEXENOATE](/api/compound/ERWcxXvcACD.png?h=300&w=458 "(-)-BENZYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-IMINO]-5-HEXENOATE")
Compound 6A (+/-)-ETHYL-2-ALLYL-3,3-DIFLUORO-2-(4-METHOXYPHENYL)-AMINO-5-HEXENOATE
Compound 6B (+/-)-BENZYL-2-ALLYL-3,3-DIFLUORO-2-(4-METHOXYPHENYL)-AMINO-5-HEXENOATE
Compound 6C (+/-)-2-(TRIMETHYLSILYL)-ETHYL-2-ALLYL-3,3-DIFLUORO-2-(4-METHOXYPHENYL)-AMINO-5-HEXENOATE
Compound 6D (+/-)-BENZYL-3,3-DIFLUORO-2-(4-METHOXYPHENYL)-AMINO-2-(2-METHYLALLYL)-5-HEXENOATE
Compound 6E BENZYL-(2R,S)-2-ALLYL-3,3-DIFLUORO-2-[[(1S)-1-PHENYLETHYL]-AMINO]-5-HEXENOATE;MAJOR-DIASTEREOMER
![BENZYL-(2R,S)-2-ALLYL-3,3-DIFLUORO-2-[[(1S)-1-PHENYLETHYL]-AMINO]-5-HEXENOATE;MAJOR-DIASTEREOMER](/api/compound/H6nKeeZwvLF.png?h=300&w=458 "BENZYL-(2R,S)-2-ALLYL-3,3-DIFLUORO-2-[[(1S)-1-PHENYLETHYL]-AMINO]-5-HEXENOATE;MAJOR-DIASTEREOMER")
Compound 6F (-)-BENZYL-(2S)-2-ALLYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE
![(-)-BENZYL-(2S)-2-ALLYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE](/api/compound/MfSuZLsb32.png?h=300&w=458 "(-)-BENZYL-(2S)-2-ALLYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE")
Compound 6G (-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-2-ALLYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-2-ALLYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE](/api/compound/KPqeMFoLldm.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-2-ALLYL-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE")
Compound 6H (-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-(2-METHYLALLYL)-5-HEXENOATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-(2-METHYLALLYL)-5-HEXENOATE](/api/compound/G9NuUFyn2sn.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-(2-METHYLALLYL)-5-HEXENOATE")
Compound 6I (-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-(1,1-DIMETHYLALLYL)-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-(1,1-DIMETHYLALLYL)-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE](/api/compound/CvMgZukv0yd.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-(1,1-DIMETHYLALLYL)-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE")
Compound 6J (-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-(2-TERT.-BUTOXYCARBONYLALLYL)-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-(2-TERT.-BUTOXYCARBONYLALLYL)-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE](/api/compound/7I7S96RxJDS.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-(2-TERT.-BUTOXYCARBONYLALLYL)-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-5-HEXENOATE")
Compound 6K (-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-2-(PHENYLALLYL)-5-HEXENOATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-2-(PHENYLALLYL)-5-HEXENOATE](/api/compound/KlHmad5n9iq.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-(2S)-3,3-DIFLUORO-2-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-2-(PHENYLALLYL)-5-HEXENOATE")
Compound 7A (+/-)-ETHYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(+/-)-ETHYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/JZdONyECFa7.png?h=300&w=458 "(+/-)-ETHYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7B (+/-)-BENZYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(+/-)-BENZYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/DiwhT6KFCmC.png?h=300&w=458 "(+/-)-BENZYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7C (+/-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(+/-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/BW9iHXdIT2R.png?h=300&w=458 "(+/-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7D (+/-)-BENZYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-METHYL-3-CYCLOHEXENE-1-CARBOXYLATE
![(+/-)-BENZYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-METHYL-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/KMVvtTuyiBB.png?h=300&w=458 "(+/-)-BENZYL-6,6-DIFLUORO-1-[(4-METHOXYPHENYL)-AMINO]-3-METHYL-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7E (-)-BENZYL-6,6-DIFLUORO-1-[[(1S)-1-PHENYLETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(-)-BENZYL-6,6-DIFLUORO-1-[[(1S)-1-PHENYLETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/JHyNpxdZYNF.png?h=300&w=458 "(-)-BENZYL-6,6-DIFLUORO-1-[[(1S)-1-PHENYLETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7F (-)-BENZYL-(1S)-6,6-DIFLUORO-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(-)-BENZYL-(1S)-6,6-DIFLUORO-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/BUh6DxuOVcU.png?h=300&w=458 "(-)-BENZYL-(1S)-6,6-DIFLUORO-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7G (-)-2-(TRIMETHYLSILYL)-ETHYL-(1S)-6,6-DIFLUORO-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-(1S)-6,6-DIFLUORO-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/IHnBp8f7JvG.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-(1S)-6,6-DIFLUORO-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7H (-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-METHYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-METHYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/1WL5mwNOU1r.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-METHYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7I (-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-2,2-DIMETHYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-2,2-DIMETHYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/1jJWSLykG0m.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-2,2-DIMETHYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7J (-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-TERT.-BUTOXYCARBONYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-TERT.-BUTOXYCARBONYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/gfxkklO3bI.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-TERT.-BUTOXYCARBONYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 7K (-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-PHENYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE
![(-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-PHENYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE](/api/compound/4YU8zHbNod1.png?h=300&w=458 "(-)-2-(TRIMETHYLSILYL)-ETHYL-6,6-DIFLUORO-3-PHENYL-1-[[(1R)-1-PHENYL-2-METHOXYETHYL]-AMINO]-3-CYCLOHEXENE-1-CARBOXYLATE")
Compound 9 (-)-2-(TRIMETHYLSILYL)-ETHYL-(1S)-1-AMINO-2,2-DIFLUOROCYCLOHEXANE-1-CARBOXYLATE
Compound 10 (+)-2-(TRIMETHYLSILYL)-ETHYL-(1S)-1-ACETAMIDO-2,2-DIFLUOROCYCLOHEXANE-1-CARBOXYLATE
Citation
| Citation | ORG.LETTERS,8,4129(2006) |
|---|---|
| Journal | Organic Letters |
| Issue | 18 |
| Volume | 8 |
| Page(s) | 4129-4132 |
| Year | 2006 |
| Author(s) | Santos Fustero, María Sánchez-Roselló, Vanessa Rodrigo, Carlos del Pozo, Juan F. Sanz-Cervera, Antonio Simón |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/ol061733c |