Spectra for:
Thilo Focken, André B. Charette
Compound SI-1 6-[(2R)-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,2,3,4-TETRAHYDROPYRIDIN-2-YL]-HEXANAL
![6-[(2R)-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,2,3,4-TETRAHYDROPYRIDIN-2-YL]-HEXANAL](/api/compound/Vr9oLVGnIh.png?h=300&w=458 "6-[(2R)-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,2,3,4-TETRAHYDROPYRIDIN-2-YL]-HEXANAL")
Compound 1 BARRENAZINE-A
Compound 2 BARRENAZINE-B
Compound 6A (2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-METHYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-METHYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/LPHKW3MGGfP.png?h=300&w=458 "(2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-METHYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6B (2R)-2-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2R)-2-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/DrAXCmxIQpO.png?h=300&w=458 "(2R)-2-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6C (2R)-2-BUTYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2R)-2-BUTYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/B7XzoJx6HDG.png?h=300&w=458 "(2R)-2-BUTYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6D (2R)-2-TERT.-BUTYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2R)-2-TERT.-BUTYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/I88fBYQBmsL.png?h=300&w=458 "(2R)-2-TERT.-BUTYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6F (2R)-2-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2R)-2-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/7srvwoVZhgz.png?h=300&w=458 "(2R)-2-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6G (1S,2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-VINYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(1S,2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-VINYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/5WGKIkYOHtE.png?h=300&w=458 "(1S,2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-VINYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6G (1S,2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-VINYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(1S,2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-VINYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/D8OvTbUIMp6.png?h=300&w=458 "(1S,2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-VINYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6H (1S,2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PROP-1-YNYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(1S,2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PROP-1-YNYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/AsF99w4sFW3.png?h=300&w=458 "(1S,2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PROP-1-YNYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6H (1S,2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PROP-1-YNYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(1S,2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PROP-1-YNYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/8iIHy5OsutN.png?h=300&w=458 "(1S,2R)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PROP-1-YNYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6I (2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-(PHENYLETHYNYL)-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-(PHENYLETHYNYL)-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/FlSfzU9l4tX.png?h=300&w=458 "(2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-(PHENYLETHYNYL)-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6J (2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PHENYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PHENYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/1niPlj2fUeJ.png?h=300&w=458 "(2S)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2-PHENYL-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 6K (2S)-2-(2-FURYL)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2S)-2-(2-FURYL)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/5g4DQfw67o3.png?h=300&w=458 "(2S)-2-(2-FURYL)-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 7A (2R)-2-ETHYL-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2R)-2-ETHYL-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/LJq898EzKNB.png?h=300&w=458 "(2R)-2-ETHYL-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 7C (2R)-2-(6-HYDROXYHEXYL)-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2R)-2-(6-HYDROXYHEXYL)-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/EmhbNeUhOfK.png?h=300&w=458 "(2R)-2-(6-HYDROXYHEXYL)-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 8 (2R)-2-HEPT-6-ENYL-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![(2R)-2-HEPT-6-ENYL-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/FSG3CX9p7UB.png?h=300&w=458 "(2R)-2-HEPT-6-ENYL-5-IODO-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
Compound 9A TERT.-BUTYL-(6R)-6-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,4,5,6-TETRAHYDROPYRIDIN-3-YLCARBAMATE
![TERT.-BUTYL-(6R)-6-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,4,5,6-TETRAHYDROPYRIDIN-3-YLCARBAMATE](/api/compound/FDf3FxYkpV5.png?h=300&w=458 "TERT.-BUTYL-(6R)-6-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,4,5,6-TETRAHYDROPYRIDIN-3-YLCARBAMATE")
Compound 10A TERT.-BUTYL-(3R,6R)-6-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXOPIPERIDIN-3-YLCARBAMATE
![TERT.-BUTYL-(3R,6R)-6-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXOPIPERIDIN-3-YLCARBAMATE](/api/compound/ANyQBZM9NY4.png?h=300&w=458 "TERT.-BUTYL-(3R,6R)-6-ETHYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXOPIPERIDIN-3-YLCARBAMATE")
Compound 10B TERT.-BUTYL-(3R,6R)-6-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXOPIPERIDIN-3-YLCARBAMATE
![TERT.-BUTYL-(3R,6R)-6-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXOPIPERIDIN-3-YLCARBAMATE](/api/compound/C9y16lAVYM2.png?h=300&w=458 "TERT.-BUTYL-(3R,6R)-6-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXOPIPERIDIN-3-YLCARBAMATE")
Compound 13 DI-TERT.-BUTYL-(3R,8R):3,8-DIETHYL-1,3,4,6,8,9-HEXAHYDRODIPYRIDO-(3,4-B:3',4'-E)-PYRAZINE-2,7-DICARBOXYLATE
Compound 14 (4S)-4-Isopropyl-2-phenyl-4,5-dihydro-1,3-oxazole
Compound 15A (-)-BARRENAZINE-A.2TFA
Compound 15B (-)-BARRENAZINE-B.2TFA
Compound 16 (3R,8R)-1,2,3,4,6,7,8,9-OCTAHYDRO-3,8-DODECANODIPYRIDO-(3,4-B:3',4'-E)-PYRAZINE-BIS-(TRIFLUOROACETATE)
#11A;N-[(1E)-[(3R,8R)-3,8-DIETHYL-7-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-3,4,6,7,8,9-HEXAHYDRODIPYRIDO-(3,4-B:3',4'-E)-PYRAZIN
![#11A;N-[(1E)-[(3R,8R)-3,8-DIETHYL-7-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-3,4,6,7,8,9-HEXAHYDRODIPYRIDO-(3,4-B:3',4'-E)-PYRAZIN](/api/compound/E1OIxbXOxyq.png?h=300&w=458 "#11A;N-[(1E)-[(3R,8R)-3,8-DIETHYL-7-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-3,4,6,7,8,9-HEXAHYDRODIPYRIDO-(3,4-B:3',4'-E)-PYRAZIN")
#11B;N-[(1E)-[(3R,8R)-3,8-DIHEPT-6-ENYL-7-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-3,4,6,7,8,9-HEXAHYDRODIPYRIDO-(3,4-B:3',
![#11B;N-[(1E)-[(3R,8R)-3,8-DIHEPT-6-ENYL-7-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-3,4,6,7,8,9-HEXAHYDRODIPYRIDO-(3,4-B:3',](/api/compound/6h9LUU2MMmD.png?h=300&w=458 "#11B;N-[(1E)-[(3R,8R)-3,8-DIHEPT-6-ENYL-7-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-3,4,6,7,8,9-HEXAHYDRODIPYRIDO-(3,4-B:3',")
#6E;(2R)-2-[6-[(TERT.-BUTYL-(DIMETHYL)-SILYL)-OXY]-HEXYL]-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE
![#6E;(2R)-2-[6-[(TERT.-BUTYL-(DIMETHYL)-SILYL)-OXY]-HEXYL]-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE](/api/compound/6sgeTBCo4go.png?h=300&w=458 "#6E;(2R)-2-[6-[(TERT.-BUTYL-(DIMETHYL)-SILYL)-OXY]-HEXYL]-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-2,3-DIHYDROPYRIDIN-4(1H)-ONE")
#9B;TERT.-BUTYL-(6R)-6-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,4,5,6-TETRAHYDROPYRIDIN-3-YLCARBAMATE
![#9B;TERT.-BUTYL-(6R)-6-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,4,5,6-TETRAHYDROPYRIDIN-3-YLCARBAMATE](/api/compound/L1w1T6vyzPl.png?h=300&w=458 "#9B;TERT.-BUTYL-(6R)-6-HEPT-6-ENYL-1-[(E)-[[(1S)-1-(METHOXYMETHYL)-2-METHYLPROPYL]-IMINO]-(PHENYL)-METHYL]-4-OXO-1,4,5,6-TETRAHYDROPYRIDIN-3-YLCARBAMATE")
Citation
| Citation | ORG.LETTERS,8,2985(2006) |
|---|---|
| Journal | Organic Letters |
| Issue | 14 |
| Volume | 8 |
| Page(s) | 2985-2988 |
| Year | 2006 |
| Author(s) | Thilo Focken, André B. Charette |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/ol0609006 |