Spectra for:
Peter G. Goekjian, Guo-Zhang Wu, Shi Chen, Lanxin Zhou, Michael R. Jirousek, James R. Gillig, Lawrence M. Ballas, Jeffrey T. Dixon
Compound 7A ETHYL-(2-R,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-HYDROXYPROPANOATE
![ETHYL-(2-R,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-HYDROXYPROPANOATE](/api/compound/IZdyNbhgzO7.png?h=300&w=458 "ETHYL-(2-R,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-HYDROXYPROPANOATE")
Compound 7B ETHYL-(2-S,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-HYDROXYPROPANOATE
![ETHYL-(2-S,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-HYDROXYPROPANOATE](/api/compound/CCut7eQiUsi.png?h=300&w=458 "ETHYL-(2-S,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-HYDROXYPROPANOATE")
Compound 8A ETHYL-(2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUOROPROPANOATE
![ETHYL-(2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUOROPROPANOATE](/api/compound/AroCefohx6K.png?h=300&w=458 "ETHYL-(2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUOROPROPANOATE")
Compound 8B ETHYL-(2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUOROPROPANOATE
![ETHYL-(2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUOROPROPANOATE](/api/compound/GmEEo7clE0W.png?h=300&w=458 "ETHYL-(2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUOROPROPANOATE")
Compound 9A (2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-(R,S)-FLUOROPROPAN-1-OL
![(2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-(R,S)-FLUOROPROPAN-1-OL](/api/compound/33xT1eeQ4yS.png?h=300&w=458 "(2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-(R,S)-FLUOROPROPAN-1-OL")
Compound 9B (2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-(R,S)-FLUOROPROPAN-1-OL
![(2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-(R,S)-FLUOROPROPAN-1-OL](/api/compound/4rh2SoP8Ang.png?h=300&w=458 "(2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-(R,S)-FLUOROPROPAN-1-OL")
Compound 10A (2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYETHOXY)-PROPAN-1-OL
![(2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYETHOXY)-PROPAN-1-OL](/api/compound/IJmKANFLJWx.png?h=300&w=458 "(2-S,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYETHOXY)-PROPAN-1-OL")
Compound 10B (2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYETHOXY)-PROPAN-1-OL
![(2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYETHOXY)-PROPAN-1-OL](/api/compound/HiTvzclQvLn.png?h=300&w=458 "(2-R,3-R)-3-(ALLYLOXY)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYETHOXY)-PROPAN-1-OL")
Compound 14 (2-S,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYPROPOXY)-PROPAN-1-OL
![(2-S,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYPROPOXY)-PROPAN-1-OL](/api/compound/EKaUjmIrKod.png?h=300&w=458 "(2-S,3-R)-3-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-2-FLUORO-3-(2-HYDROXYPROPOXY)-PROPAN-1-OL")
#11A;(18R,19S)-18-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-19-FLUORO-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28
![#11A;(18R,19S)-18-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-19-FLUORO-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28](/api/compound/143X9g0Bozl.png?h=300&w=458 "#11A;(18R,19S)-18-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-19-FLUORO-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28")
#11B;(18R,19R)-18-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-19-FLUORO-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28
![#11B;(18R,19R)-18-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-19-FLUORO-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28](/api/compound/ARYYgASXSmW.png?h=300&w=458 "#11B;(18R,19R)-18-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-19-FLUORO-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28")
#12A;(18R,19S)-19-FLUORO-18-(HYDROXYMETHYL)-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,
![#12A;(18R,19S)-19-FLUORO-18-(HYDROXYMETHYL)-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,](/api/compound/JYqGb0qAaAI.png?h=300&w=458 "#12A;(18R,19S)-19-FLUORO-18-(HYDROXYMETHYL)-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,")
#12B;(18R,19R)-19-FLUORO-18-(HYDROXYMETHYL)-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,
![#12B;(18R,19R)-19-FLUORO-18-(HYDROXYMETHYL)-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,](/api/compound/LJOh5yNWipz.png?h=300&w=458 "#12B;(18R,19R)-19-FLUORO-18-(HYDROXYMETHYL)-4-METHYL-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,")
#15;(19R,20S)-19-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-20-FLUORO-4-METHYL-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29
![#15;(19R,20S)-19-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-20-FLUORO-4-METHYL-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29](/api/compound/AE5iicfJMfQ.png?h=300&w=458 "#15;(19R,20S)-19-[(2-R)-1,4-DIOXASPIRO-[4.5]-DECANYL]-20-FLUORO-4-METHYL-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29")
#16;(19R,20S)-20-FLUORO-19-(HYDROXYMETHYL)-4-METHYL-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,
![#16;(19R,20S)-20-FLUORO-19-(HYDROXYMETHYL)-4-METHYL-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,](/api/compound/KsT9ezMAIQ0.png?h=300&w=458 "#16;(19R,20S)-20-FLUORO-19-(HYDROXYMETHYL)-4-METHYL-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,")
#1;(18R,19S)-19-FLUORO-18-[(DIMETHYLAMINO)-METHYL]-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22
![#1;(18R,19S)-19-FLUORO-18-[(DIMETHYLAMINO)-METHYL]-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22](/api/compound/40X6gwIb2lm.png?h=300&w=458 "#1;(18R,19S)-19-FLUORO-18-[(DIMETHYLAMINO)-METHYL]-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22")
#2;(18R,19R)-19-FLUORO-18-[(DIMETHYLAMINO)-METHYL]-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22
![#2;(18R,19R)-19-FLUORO-18-[(DIMETHYLAMINO)-METHYL]-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22](/api/compound/BsKOXVUv05A.png?h=300&w=458 "#2;(18R,19R)-19-FLUORO-18-[(DIMETHYLAMINO)-METHYL]-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22")
#3;(18R,19S)-19-FLUORO-18-(HYDROXYMETHYL)-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22(27),23,2
![#3;(18R,19S)-19-FLUORO-18-(HYDROXYMETHYL)-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22(27),23,2](/api/compound/3bBJPZCBcKH.png?h=300&w=458 "#3;(18R,19S)-19-FLUORO-18-(HYDROXYMETHYL)-17-OXA-4,14,21-TRIAZAHEXACYCLO-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-NONACOSA-1(28),2(6),7(29),8,10,12,22(27),23,2")
#4;(18R,19R)-19-Fluoro-18-(hydroxymethyl)-17-oxa-4,14,21-triazahexacyclo-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-nonacosa-1(28),2(6),7(29),8,10,12,22(27),23,2
![#4;(18R,19R)-19-Fluoro-18-(hydroxymethyl)-17-oxa-4,14,21-triazahexacyclo-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-nonacosa-1(28),2(6),7(29),8,10,12,22(27),23,2](/api/compound/L1WZNsKHvud.png?h=300&w=458 "#4;(18R,19R)-19-Fluoro-18-(hydroxymethyl)-17-oxa-4,14,21-triazahexacyclo-[19.6.1.1(7,14).0(2,6).0(8,13).0(22,27)]-nonacosa-1(28),2(6),7(29),8,10,12,22(27),23,2")
#5;(19R,20S)-20-FLUORO-19-(HYDROXYMETHYL)-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,23(28),24,
![#5;(19R,20S)-20-FLUORO-19-(HYDROXYMETHYL)-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,23(28),24,](/api/compound/FHBsrgzqHsh.png?h=300&w=458 "#5;(19R,20S)-20-FLUORO-19-(HYDROXYMETHYL)-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,23(28),24,")
#6;(19R,20S)-19-[(DIMETHYLAMINO)-METHYL]-20-FLUORO-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,2
![#6;(19R,20S)-19-[(DIMETHYLAMINO)-METHYL]-20-FLUORO-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,2](/api/compound/Jh8gAXFfcGE.png?h=300&w=458 "#6;(19R,20S)-19-[(DIMETHYLAMINO)-METHYL]-20-FLUORO-18-OXA-4,14,21-TRIAZAHEXACYCLO-[20.6.1.1(7,14).0(2,6).0(8,13).0(22,28)]-TRIACONTA-1(29),2(6),7(30),8,10,12,2")
Citation
| Citation | J.ORG.CHEM.,64,4238(1999) |
|---|---|
| Journal | The Journal of Organic Chemistry |
| Issue | 12 |
| Volume | 64 |
| Page(s) | 4238-4246 |
| Year | 1999 |
| Author(s) | Peter G. Goekjian, Guo-Zhang Wu, Shi Chen, Lanxin Zhou, Michael R. Jirousek, James R. Gillig, Lawrence M. Ballas, Jeffrey T. Dixon |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jo9808876 |