Spectra for:
Thazha P. Prakash, Andrew M. Kawasaki, Allister S. Fraser, Guillermo Vasquez, Muthiah Manoharan
Compound 1 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE
![5'-O-(4,4'-DIMETHOXYTRITYL)-2'-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE](/api/compound/8q1XdiX6EG1.png?h=300&w=458 "5'-O-(4,4'-DIMETHOXYTRITYL)-2'-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE")
Compound 2 N(6)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE
![N(6)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE](/api/compound/GiSkUEpeLO1.png?h=300&w=458 "N(6)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE")
Compound 3 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE
![5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE](/api/compound/CdBPRmlSofx.png?h=300&w=458 "5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE")
Compound 3 3 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE
![5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE](/api/compound/J7KZ9IOjVuz.png?h=300&w=458 "5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE")
Compound 6 5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2,2'-ANHYDRO-5-METHYL-URIDINE
Compound 7 5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-(2-HYDROXYETHYL)-5-METHYL-URIDINE
Compound 13 2'/3'-O-ALLYL-N(6)-BENZOYL-5'-O-(TERT.-BUTYLDIPHENYLSILYL)-ADENOSINE
Compound 14 2'-O-ALLYL-GUANOSINE
Compound 15 2'-O-ALLYL-3',5'-BIS-(TERT.-BUTYLDIPHENYLSILYL)-GUANOSINE
Compound 16 N(6)-BENZOYL-5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-(2-HYDROXYETHYL)-ADENOSINE
Compound 17 2'-O-(2-HYDROXYETHYL)-3',5'-BIS-(TERT.-BUTYLDIPHENYLSILYL)-GUANOSINE
Compound 18 5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-5-METHYL-URIDINE
![5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-5-METHYL-URIDINE](/api/compound/J3Y61gNb5E0.png?h=300&w=458 "5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-5-METHYL-URIDINE")
Compound 19 N(6)-BENZOYL-5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-ADENOSINE
![N(6)-BENZOYL-5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-ADENOSINE](/api/compound/HdHUh8hWnz4.png?h=300&w=458 "N(6)-BENZOYL-5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-ADENOSINE")
Compound 20 3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-GUANOSINE
![3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-GUANOSINE](/api/compound/HhQmO45f9bc.png?h=300&w=458 "3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-OXY]-ETHYL]-GUANOSINE")
Compound 22 5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(METHYLENEAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE
![5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(METHYLENEAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE](/api/compound/EbrzFGSMSOJ.png?h=300&w=458 "5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(METHYLENEAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE")
Compound 23 N(6)-BENZOYL-(5'-O-TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(METHYLENEAMINO)-OXY]-ETHYL]-ADENOSINE
![N(6)-BENZOYL-(5'-O-TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(METHYLENEAMINO)-OXY]-ETHYL]-ADENOSINE](/api/compound/DhopmjZ783o.png?h=300&w=458 "N(6)-BENZOYL-(5'-O-TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(METHYLENEAMINO)-OXY]-ETHYL]-ADENOSINE")
Compound 25 5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE
![5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE](/api/compound/D8T2vsb0enh.png?h=300&w=458 "5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE")
Compound 26 N(6)-BENZOYL-5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE
![N(6)-BENZOYL-5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE](/api/compound/CKLPxN5A6d4.png?h=300&w=458 "N(6)-BENZOYL-5'-O-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE")
Compound 27 3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE
![3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE](/api/compound/Da92D0zeMlm.png?h=300&w=458 "3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE")
Compound 28 2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE
![2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE](/api/compound/JGnDTt4Xewb.png?h=300&w=458 "2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE")
Compound 29 N(6)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE
![N(6)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE](/api/compound/6BuK6zkKkJa.png?h=300&w=458 "N(6)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE")
Compound 30 2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE
![2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE](/api/compound/HgFvqUHDqjq.png?h=300&w=458 "2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-N(2)-ISOBUTYRYL-GUANOSINE")
Compound 31 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE
![5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE](/api/compound/7v8uLKsiXYw.png?h=300&w=458 "5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE")
Compound 32 N(6)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE
![N(6)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE](/api/compound/AAtDi2wVlO4.png?h=300&w=458 "N(6)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE")
Compound 34 3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE
![3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE](/api/compound/9EtuSEG32ER.png?h=300&w=458 "3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE")
Compound 35 3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE
![3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE](/api/compound/9UcpN5Y3s8r.png?h=300&w=458 "3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE")
Compound 36 N(4)-BENZOYL-3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE
![N(4)-BENZOYL-3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE](/api/compound/3SwqvwGjJN8.png?h=300&w=458 "N(4)-BENZOYL-3',5'-O-BIS-(TERT.-BUTYLDIPHENYLSILYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE")
Compound 37 N(4)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE
![N(4)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE](/api/compound/7lk4dQxZz7S.png?h=300&w=458 "N(4)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE")
Compound 38 N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE
![N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE](/api/compound/KVSFSosxn81.png?h=300&w=458 "N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE")
Compound 39 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE-3'-O-SUCCINATE
![5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE-3'-O-SUCCINATE](/api/compound/2zloPLjqPJu.png?h=300&w=458 "5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-URIDINE-3'-O-SUCCINATE")
Compound 40 5'-O-(4,4'-DIMETHOXYTRITYL)-N(6)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE-3'-O-SUCCINATE
![5'-O-(4,4'-DIMETHOXYTRITYL)-N(6)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE-3'-O-SUCCINATE](/api/compound/4L2qosK8yXa.png?h=300&w=458 "5'-O-(4,4'-DIMETHOXYTRITYL)-N(6)-BENZOYL-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-ADENOSINE-3'-O-SUCCINATE")
Compound 41 N(2)-IZOBUTYRYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-GUANOSINE-3'-O-SUCCINATE
![N(2)-IZOBUTYRYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-GUANOSINE-3'-O-SUCCINATE](/api/compound/Gdxzdu86wcU.png?h=300&w=458 "N(2)-IZOBUTYRYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-GUANOSINE-3'-O-SUCCINATE")
Compound 42 N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE-3'-O-SUCCINATE
![N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE-3'-O-SUCCINATE](/api/compound/Kl66wv9og2L.png?h=300&w=458 "N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE-3'-O-SUCCINATE")
#4;N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE
![#4;N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE](/api/compound/IANovzfNSzh.png?h=300&w=458 "#4;N(4)-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-[2-[(N,N-DIMETHYLAMINO)-OXY]-ETHYL]-5-METHYL-CYTIDINE-3'-[(2-CYANOETHYL)-N,N-DIISOPROPYL]-PHOSPHORAMIDITE")
Citation
| Citation | J.ORG.CHEM.,67,357(2002) |
|---|---|
| Journal | The Journal of Organic Chemistry |
| Issue | 2 |
| Volume | 67 |
| Page(s) | 357-369 |
| Year | 2001 |
| Author(s) | Thazha P. Prakash, Andrew M. Kawasaki, Allister S. Fraser, Guillermo Vasquez, Muthiah Manoharan |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jo0103975 |