Spectra for:
José I. Borrell, Jordi Teixidó, Josep Lluís Matallana, Blanca Martínez-Teipel, Carles Colominas, Marta Costa, Merche Balcells, Elisabeth Schuler, María José Castillo
Compound 13A DIMETHYL-2-CYANO-4-[[(4-METHOXYCARBONYLPHENYL)-METHYLAMINO]-METHYL]-PENTANEDIOATE
![DIMETHYL-2-CYANO-4-[[(4-METHOXYCARBONYLPHENYL)-METHYLAMINO]-METHYL]-PENTANEDIOATE](/api/compound/1TbqRqG4SVd.png?h=300&w=458 "DIMETHYL-2-CYANO-4-[[(4-METHOXYCARBONYLPHENYL)-METHYLAMINO]-METHYL]-PENTANEDIOATE")
Compound 13B DIMETHYL-2-CYANO-4-(4-METHOXYCARBONYLPHENYL-AMINOMETHYL)-PENTANEDIOATE
Compound 13C DIMETHYL-2-CYANO-4-[2-(4-METHOXYCARBONYLPHENYL)-ETHYL]-PENTANEDIOATE
![DIMETHYL-2-CYANO-4-[2-(4-METHOXYCARBONYLPHENYL)-ETHYL]-PENTANEDIOATE](/api/compound/AaM8epZdZOS.png?h=300&w=458 "DIMETHYL-2-CYANO-4-[2-(4-METHOXYCARBONYLPHENYL)-ETHYL]-PENTANEDIOATE")
Compound 14A METHYL-4-[(4,4-DICYANO-2-METHOXYCARBONYLBUTYL)-METHYLAMINO]-BENZOATE
![METHYL-4-[(4,4-DICYANO-2-METHOXYCARBONYLBUTYL)-METHYLAMINO]-BENZOATE](/api/compound/4SbvH6afjiA.png?h=300&w=458 "METHYL-4-[(4,4-DICYANO-2-METHOXYCARBONYLBUTYL)-METHYLAMINO]-BENZOATE")
Compound 14B METHYL-4-(4,4-DICYANO-2-METHOXYCARBONYLBUTYLAMINO)-BENZOATE
Compound 14C METHYL-4-(5,5-DICYANO-3-METHOXYCARBONYLPENTYL)-BENZOATE
Compound 15A METHYL-4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOATE
![METHYL-4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOATE](/api/compound/BKtEmkFOkk8.png?h=300&w=458 "METHYL-4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOATE")
Compound 15B METHYL-4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOATE
![METHYL-4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOATE](/api/compound/FkEvd7nbzRv.png?h=300&w=458 "METHYL-4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOATE")
Compound 15C METHYL-4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOATE
![METHYL-4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOATE](/api/compound/mbZRUaCge1.png?h=300&w=458 "METHYL-4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOATE")
Compound 16A 4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOIC-ACID
![4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOIC-ACID](/api/compound/BORucV3hGuj.png?h=300&w=458 "4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOIC-ACID")
Compound 16B 4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOIC-ACID
![4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOIC-ACID](/api/compound/3RosvzU55It.png?h=300&w=458 "4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOIC-ACID")
Compound 16C 4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOIC-ACID
![4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOIC-ACID](/api/compound/5wrPKQVD9ou.png?h=300&w=458 "4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOIC-ACID")
Compound 17A DIMETHYL-N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOYL]-L-GLUTAMATE
![DIMETHYL-N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOYL]-L-GLUTAMATE](/api/compound/FBmsB65W6Ho.png?h=300&w=458 "DIMETHYL-N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOYL]-L-GLUTAMATE")
Compound 17B DIMETHYL-N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOYL]-L-GLUTAMATE
![DIMETHYL-N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOYL]-L-GLUTAMATE](/api/compound/75m3xUaPAyh.png?h=300&w=458 "DIMETHYL-N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOYL]-L-GLUTAMATE")
Compound 17C DIMETHYL-N-[4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOYL]-L-GLUTAMATE
![DIMETHYL-N-[4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOYL]-L-GLUTAMATE](/api/compound/BC5mLKMAuVS.png?h=300&w=458 "DIMETHYL-N-[4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOYL]-L-GLUTAMATE")
Compound 18A N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOYL]-L-GLUTAMIC-ACID
![N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOYL]-L-GLUTAMIC-ACID](/api/compound/9j0nxZfuQPc.png?h=300&w=458 "N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-N-METHYLAMINO]-BENZOYL]-L-GLUTAMIC-ACID")
Compound 18B N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOYL]-L-GLUTAMIC-ACID
![N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOYL]-L-GLUTAMIC-ACID](/api/compound/FKlQVOIHXwJ.png?h=300&w=458 "N-[4-[N-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YLMETHYL)-AMINO]-BENZOYL]-L-GLUTAMIC-ACID")
Compound 18C N-[4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOYL]-L-GLUTAMIC-ACID
![N-[4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOYL]-L-GLUTAMIC-ACID](/api/compound/Keon7HG08ow.png?h=300&w=458 "N-[4-[2-(2-AMINO-4,7-DIOXO-3,4,5,6,7,8-HEXAHYDROPYRIDO-[2,3-D]-PYRIMIDIN-6-YL)-ETHYL]-BENZOYL]-L-GLUTAMIC-ACID")
Compound 19A DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[[N-(4-METHOXYCARBONYLPHENYL)-N-METHYLAMINO]-METHYL]-HEPTANODIOATE
![DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[[N-(4-METHOXYCARBONYLPHENYL)-N-METHYLAMINO]-METHYL]-HEPTANODIOATE](/api/compound/5GM2Gct6Dex.png?h=300&w=458 "DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[[N-(4-METHOXYCARBONYLPHENYL)-N-METHYLAMINO]-METHYL]-HEPTANODIOATE")
Compound 19B DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[N-(4-METHOXYCARBONYLPHENYL)-AMINOMETHYL]-HEPTANODIOATE
![DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[N-(4-METHOXYCARBONYLPHENYL)-AMINOMETHYL]-HEPTANODIOATE](/api/compound/6EZIUzCz3JB.png?h=300&w=458 "DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[N-(4-METHOXYCARBONYLPHENYL)-AMINOMETHYL]-HEPTANODIOATE")
Compound 19C DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[2-(4-METHOXYCARBONYLPHENYL)-ETHYL]-HEPTANODIOATE
![DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[2-(4-METHOXYCARBONYLPHENYL)-ETHYL]-HEPTANODIOATE](/api/compound/FspE2udSHRP.png?h=300&w=458 "DIMETHYL-4-CYANO-4-METHOXYCARBONYL-2,6-BIS-[2-(4-METHOXYCARBONYLPHENYL)-ETHYL]-HEPTANODIOATE")
Compound 20A 4-[[2-CARBOXY-3-(2,4-DIAMINO-6-OXO-1,6-DIHYDROPYRIMIDIN-5-YL)-PROPYL]-METHYLAMINO]-BENZOIC-ACID
![4-[[2-CARBOXY-3-(2,4-DIAMINO-6-OXO-1,6-DIHYDROPYRIMIDIN-5-YL)-PROPYL]-METHYLAMINO]-BENZOIC-ACID](/api/compound/3TZEOIj25nA.png?h=300&w=458 "4-[[2-CARBOXY-3-(2,4-DIAMINO-6-OXO-1,6-DIHYDROPYRIMIDIN-5-YL)-PROPYL]-METHYLAMINO]-BENZOIC-ACID")
Compound 20B 4-[2-CARBOXY-3-(2,4-DIAMINO-6-OXO-1,6-DIHYDROPYRIMIDIN-5-YL)-PROPYL]-AMINOBENZOIC-ACID
![4-[2-CARBOXY-3-(2,4-DIAMINO-6-OXO-1,6-DIHYDROPYRIMIDIN-5-YL)-PROPYL]-AMINOBENZOIC-ACID](/api/compound/Ih9mqXdNA8V.png?h=300&w=458 "4-[2-CARBOXY-3-(2,4-DIAMINO-6-OXO-1,6-DIHYDROPYRIMIDIN-5-YL)-PROPYL]-AMINOBENZOIC-ACID")
Citation
| Citation | J.MED.CHEM.,44,2366(2001) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 14 |
| Volume | 44 |
| Page(s) | 2366-2369 |
| Year | 2001 |
| Author(s) | José I. Borrell, Jordi Teixidó, Josep Lluís Matallana, Blanca Martínez-Teipel, Carles Colominas, Marta Costa, Merche Balcells, Elisabeth Schuler, María José Castillo |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm990411u |