Spectra for:
T. Santhosh Kumar, Si-Yuan Zhou, Bhalchandra V. Joshi, Ramachandran Balasubramanian, Tiehong Yang, Bruce T. Liang, Kenneth A. Jacobson
Compound 4 X1(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOMETHYLENE)-BICYCLO-[3.1.0]-HEXANE
![X1(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOMETHYLENE)-BICYCLO-[3.1.0]-HEXANE](/api/compound/EcT3wWLizFh.png?h=300&w=458 "X1(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOMETHYLENE)-BICYCLO-[3.1.0]-HEXANE")
Compound 5 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOMETHYLENE)-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOMETHYLENE)-BICYCLO-[3.1.0]-HEXANE](/api/compound/Fcx43o4FoIq.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOMETHYLENE)-BICYCLO-[3.1.0]-HEXANE")
Compound 7 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-[(E)-PHOSPHONOETHENYL]-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-[(E)-PHOSPHONOETHENYL]-BICYCLO-[3.1.0]-HEXANE](/api/compound/AxtWWx4bbZj.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-[(E)-PHOSPHONOETHENYL]-BICYCLO-[3.1.0]-HEXANE")
Compound 8 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-[(E)-PHOSPHONOETHENYL]-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-[(E)-PHOSPHONOETHENYL]-BICYCLO-[3.1.0]-HEXANE](/api/compound/GRTSgmtQ4bh.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-[(E)-PHOSPHONOETHENYL]-BICYCLO-[3.1.0]-HEXANE")
Compound 9 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOETHENYL)-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOETHENYL)-BICYCLO-[3.1.0]-HEXANE](/api/compound/JmD3LANIuc5.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOETHENYL)-BICYCLO-[3.1.0]-HEXANE")
Compound 10 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOETHENYL)-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOETHENYL)-BICYCLO-[3.1.0]-HEXANE](/api/compound/5Po4THgbWFS.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(PHOSPHONOETHENYL)-BICYCLO-[3.1.0]-HEXANE")
Compound 11 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(METHYLPHOSPHONIC_ACID)-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(METHYLPHOSPHONIC_ACID)-BICYCLO-[3.1.0]-HEXANE](/api/compound/EyoXVPrZgYG.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINO-2-CHLOROPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(METHYLPHOSPHONIC_ACID)-BICYCLO-[3.1.0]-HEXANE")
Compound 12 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(METHYLPHOSPHONIC_ACID)-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(METHYLPHOSPHONIC_ACID)-BICYCLO-[3.1.0]-HEXANE](/api/compound/K8yJEnmuWQW.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-2',3'-(DIHYDROXY)-1'-(METHYLPHOSPHONIC_ACID)-BICYCLO-[3.1.0]-HEXANE")
Compound 18 DIETHYL-(1-S,2-R,3-S,4-S,5-S)-2,3-O-(ISOPROPYLIDENE)-4-O-(TERT.-BUTYLDIMETHYLSILYL)-BICYCLO-[3.1.0]-HEXANE_PHOSPHONATE
![DIETHYL-(1-S,2-R,3-S,4-S,5-S)-2,3-O-(ISOPROPYLIDENE)-4-O-(TERT.-BUTYLDIMETHYLSILYL)-BICYCLO-[3.1.0]-HEXANE_PHOSPHONATE](/api/compound/BIpyE84kotT.png?h=300&w=458 "DIETHYL-(1-S,2-R,3-S,4-S,5-S)-2,3-O-(ISOPROPYLIDENE)-4-O-(TERT.-BUTYLDIMETHYLSILYL)-BICYCLO-[3.1.0]-HEXANE_PHOSPHONATE")
Compound 19 DIETHYL-(1-S,2-R,3-S,4-S,5-S)-4-HYDROXY-2,3-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE_PHOSPHONATE
![DIETHYL-(1-S,2-R,3-S,4-S,5-S)-4-HYDROXY-2,3-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE_PHOSPHONATE](/api/compound/6dI0f3AXIC7.png?h=300&w=458 "DIETHYL-(1-S,2-R,3-S,4-S,5-S)-4-HYDROXY-2,3-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE_PHOSPHONATE")
Compound 26 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(2,6-DICHLOROPURIN-9-YL)-1'-[DIISOPROPYL-(E)-ETHENYLPHOSPHONATE]-2',3'-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(2,6-DICHLOROPURIN-9-YL)-1'-[DIISOPROPYL-(E)-ETHENYLPHOSPHONATE]-2',3'-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE](/api/compound/8VAH2R0VkTJ.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(2,6-DICHLOROPURIN-9-YL)-1'-[DIISOPROPYL-(E)-ETHENYLPHOSPHONATE]-2',3'-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE")
Compound 28 (1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-1'-(DIISOPROPYLPHOSPHONOETHENYL)-2',3'-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE
![(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-1'-(DIISOPROPYLPHOSPHONOETHENYL)-2',3'-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE](/api/compound/IT0MWi4pbNa.png?h=300&w=458 "(1'-S,2'-R,3'-S,4'-R,5'-S)-4'-(6-AMINOPURIN-9-YL)-1'-(DIISOPROPYLPHOSPHONOETHENYL)-2',3'-O-(ISOPROPYLIDENE)-BICYCLO-[3.1.0]-HEXANE")
Citation
| Citation | J.MED.CHEM.,53,2562(2010) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 6 |
| Volume | 53 |
| Page(s) | 2562-2576 |
| Year | 2010 |
| Author(s) | T. Santhosh Kumar, Si-Yuan Zhou, Bhalchandra V. Joshi, Ramachandran Balasubramanian, Tiehong Yang, Bruce T. Liang, Kenneth A. Jacobson |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm9018542 |