Spectra for:
Alexander Breuning, Bj�rn Degel, Franziska Schulz, Christian B�chold, Martin Stempka, Uwe Machon, Saskia Heppner, Christoph Gelhaus, Matthias Leippe, Matthias Leyh, Caroline Kisker, Jennifer Rath, August Stich, Jiri Gut, Philip J. Rosenthal, Carsten Schmuck, Tanja Schirmeister
Compound 4 4-AMINO-2-(TERT.-BUTOXYCARBONYLAMINO)-4-OXOBUTYL_ETHYL-FUMARATE
Compound 5 (S)-5-AMINO-2-(TERT.-BUTOXYCARBONYLAMINO)-5-OXOPENTYLT_ETHYL_FUMARATE
Compound 6 (S)-4-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-2-PHENYLACETAMIDO)-4-OXOBUTYL_ETHYL_FUMARATE
Compound 7 (S)-5-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-2-PHENYLACETAMIDO)-5-OXOBUTYL_ETHYL_FUMARATE
Compound 8 (S,E)-ETHYL_4-(4-AMINO-1-TERT.-BUTOXY-1,4-DIOXOBUTYN-2-YLAMINO)-4-OXOBUT-2-ENOATE
Compound 9 (E)-3-[(S)-1-METHOXYCARBONYL-2-(TRITYL-CARBAMOYL)-ETHYLCARBOMOYL]-ACRYLIC_ACID_ETHYLESTER
![(E)-3-[(S)-1-METHOXYCARBONYL-2-(TRITYL-CARBAMOYL)-ETHYLCARBOMOYL]-ACRYLIC_ACID_ETHYLESTER](/api/compound/4suXx1fBsTG.png?h=300&w=458 "(E)-3-[(S)-1-METHOXYCARBONYL-2-(TRITYL-CARBAMOYL)-ETHYLCARBOMOYL]-ACRYLIC_ACID_ETHYLESTER")
Compound 10 (S,E)-TERT.-BUTYL-5-AMINO-2-(4-ETHOXY-4-OXOBUT-2-ENAMIDO)-5-OXOPENTANOATE
Compound 11 (S,E)-METHYL_2-(4-ETHOXY-4-OXOBUT-2-ENAMIDO)-5-OXO-5-(TRITYLAMINO)-PENTANOATE
Compound 12 (S,E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLIC_ACID_ETHYLESTER
Compound 13 (E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLIC_ACID
Compound 14 (S)-2-[(E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYL-ETHYLCARBAMOYL)-ACRYLOYL-AMINO]-3-PHENYLPROPIONIC_ACID_BENYLESTER
![(S)-2-[(E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYL-ETHYLCARBAMOYL)-ACRYLOYL-AMINO]-3-PHENYLPROPIONIC_ACID_BENYLESTER](/api/compound/9jjQrYQVwSt.png?h=300&w=458 "(S)-2-[(E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYL-ETHYLCARBAMOYL)-ACRYLOYL-AMINO]-3-PHENYLPROPIONIC_ACID_BENYLESTER")
Compound 16A (S,E)-ETHYL-4-((S/R)-2-(TERT.-BUTOXYCARBONYLAMINO)-2-PHENYLACETAMIDO)-7-OXO-7-(TRITYLAMINO)-HEPT-2-ENOATE;MAJOR_ISOMER
Compound 17 (S,E)-ETHYL_4-(4-AMINO-1-TERT.-BUTOXYCARBONYL-1,4-DIOXOBUTAN-2-YLAMINO)-BUT-2-ENOATE
Compound 18 (S,E)-TERT.-BUTYL_5-AMINO-2-(4-ETHOXY-4-OXOBUT-2-ENYLAMINO)-5-OXOPENTANOATE
Compound 19 (S,E)-ETHYL-4-(1-BENZYLOXYCARBONYL-2-PHENYLETHYLAMINO)-BUT-2-ENOATE
Compound 20 (2-S,5-S,8-S,11-S,E)-1-BENZYL_16-ETHYL_11-(3-AMINO-3-OXOPROPYL)-8-CYCLOHEXYL-5-ISOPROPYL-2-METHYL-4,7,10-TRIOXO-3,6,9,12-TETRAAZAHEXADEC-14-ENE-1,
Compound 21 (S,E)-ETHYL-3-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-4-CARBAMOYL-BUTOXY]-ACRYLATE
![(S,E)-ETHYL-3-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-4-CARBAMOYL-BUTOXY]-ACRYLATE](/api/compound/DUjNJcQngXi.png?h=300&w=458 "(S,E)-ETHYL-3-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-4-CARBAMOYL-BUTOXY]-ACRYLATE")
Compound 22 (Z)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;CIS-ISOMER
![(Z)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;CIS-ISOMER](/api/compound/51oV5qwlm83.png?h=300&w=458 "(Z)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;CIS-ISOMER")
Compound 22 (E)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;TRANS_ISOMER
![(E)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;TRANS_ISOMER](/api/compound/4rsPcySj59g.png?h=300&w=458 "(E)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;TRANS_ISOMER")
Compound 23 (S)-4-TERT.-BUTYL_5-AMINO-2-(3-ETHOXY-3-OXOPROP-1-ENYLAMINO)-5-OXOPENTANOATE;CIS_ISOMER
Compound 23 (S)-4-TERT.-BUTYL_5-AMINO-2-(3-ETHOXY-3-OXOPROP-1-ENYLAMINO)-5-OXOPENTANOATE;TRANS_ISOMER
Compound 24 (S,E)-ETHYL_4-(4-AMINO-2-(TERT.-BUTOXYCARBONYLAMINO)-4-OXOBUTAMOYLOXY)-BUT-2-ENOATE
Compound 25 (S,E)-4-ETHOXY-4-OXOBUT-2-ENYL_5-AMINO-2-(TERT.-BUTOXYCARBONYLAMINO)-5-OXOPENTANOATE
Compound 26 (E)-ETHYL-4-((S)-4-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-4-METHYLPENTANAMIDO)-4-OXOBUTANOYLOXY)-BUT-2-ENOATE
Compound 27 (E)-ETHYL_4-((S)-4-AMINO-2-((S)-(TERT.-BUTOXYCARBONYLAMINO)-2-CYCLOHEXYLACETAMIDO)-4-OXOBUTANOYLOXY)-BUT-2-ENOATE
Compound 28 (S)-((E)-4-ETHOXY-4-OXOBUT-2-ENYL)-5-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-4-METHYLPENTANAMIDO)-5-OXOPENTANOATE
Compound 29 (S)-((E)-4-ETHOXY-4-OXOBUT-2-ENYL)-5-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-2-CYCLOHEXYLACETAMIDO)-5-OXOPENTANOATE
Compound 30 (6-S,9-S,12-S)-((E)-4-ETHOXY-4-OXOBUT-2-ENYL)_12-(3-AMINO-3-OXOPROPYL)-9-ISOBUTYL-2,2,6-TRIMETHYL-4,7,10-TRIOXO-3-OXA-5,8,11-TRIAZATRIDECAN-13-OAT
Compound 31 (2-S,5-S,8-S,11-S,E)-1-AMIDE_16-HYDROXY-11-(3-AMINO-3-OXOPROPYL)-8-(2-METHYLPROPYL)-5-ISOPROPYL-2-ISOPROPYL-4,7,10,13-TETRAOXO-3,6,9,12-TETRAAZAHE
Compound 32 (S,E)-BENZYL-2-(BUT-2-ENOYLAMINO)-3-PHENYLPROPIONATE
Compound 33 (S,E)-ETHYL_5-(2-BENZYLOXYCARBONYLAMINO-3-PHENYLPROPIONYLOXY)-PENT-2-ENOATE
Compound 34 (Z)-BUT-2-ENDIOIC_ACID-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-3-PHENYLPROPYLESTER]-ETHYLESTER
![(Z)-BUT-2-ENDIOIC_ACID-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-3-PHENYLPROPYLESTER]-ETHYLESTER](/api/compound/EbC6fX0gwAH.png?h=300&w=458 "(Z)-BUT-2-ENDIOIC_ACID-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-3-PHENYLPROPYLESTER]-ETHYLESTER")
Compound 35 (S)-2-((Z)-3-ETHOXYCARBONYL-ACRYLOYLAMINO)-4-(TRITYL-CARBAMOYL)-BUTYRIC_ACID_METHYLESTER
Compound 37 (Z)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLIC_ACID
Compound 39 (Z)-3-[(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLIC_ACID
![(Z)-3-[(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLIC_ACID](/api/compound/BIiIMds0o6z.png?h=300&w=458 "(Z)-3-[(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLIC_ACID")
Compound 41 (S)-BENZYL-2-{(S)-2-[(S)-2-((Z)-3-CARBOXY-ACRYLOYLAMINO)-3-PEHNYLPROPIONYLAMINO]-PROPIONYLAMINO}-4-METHYLPENTANOATE
![(S)-BENZYL-2-{(S)-2-[(S)-2-((Z)-3-CARBOXY-ACRYLOYLAMINO)-3-PEHNYLPROPIONYLAMINO]-PROPIONYLAMINO}-4-METHYLPENTANOATE](/api/compound/JSluiaJVlu7.png?h=300&w=458 "(S)-BENZYL-2-{(S)-2-[(S)-2-((Z)-3-CARBOXY-ACRYLOYLAMINO)-3-PEHNYLPROPIONYLAMINO]-PROPIONYLAMINO}-4-METHYLPENTANOATE")
Compound 42 (S)-BENZYL-2-[(Z)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLOYL-AINO]-3-PHENYLPROPIONATE
![(S)-BENZYL-2-[(Z)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLOYL-AINO]-3-PHENYLPROPIONATE](/api/compound/CmNgmRfKz2U.png?h=300&w=458 "(S)-BENZYL-2-[(Z)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLOYL-AINO]-3-PHENYLPROPIONATE")
Compound 43 (S)-BENZYL-2-{/Z)-3-(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLOYLAMINO}-3-PHENYLPROPIONATE
![(S)-BENZYL-2-{/Z)-3-(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLOYLAMINO}-3-PHENYLPROPIONATE](/api/compound/6vtufbthwPd.png?h=300&w=458 "(S)-BENZYL-2-{/Z)-3-(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLOYLAMINO}-3-PHENYLPROPIONATE")
Compound 44 (S,Z)-ETHYL-4-TERT.-BUTOXYCARBONYLAMINO-5-PEHNYLPENT-2-ENOATE
Compound 45 (S,Z)-ETHYL-4-(2-TERT.-BUTOXYCARBONYLAMINO-3-PHENYLPROPIONYLAMINO)-BUT-2-ENOATE
(E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLIC_ACID_TERT.-BUTYLESTER
(Z)-ETHYL-4-TERT.-BUTOXYCARBONYLAMINOBUT-2-ENOATE
Citation
| Citation | J.MED.CHEM.,53,1951(2010) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 5 |
| Volume | 53 |
| Page(s) | 1951-1963 |
| Year | 2010 |
| Author(s) | Alexander Breuning, Bj�rn Degel, Franziska Schulz, Christian B�chold, Martin Stempka, Uwe Machon, Saskia Heppner, Christoph Gelhaus, Matthias Leippe, Matthias Leyh, Caroline Kisker, Jennifer Rath, August Stich, Jiri Gut, Philip J. Rosenthal, Carsten Schmuck, Tanja Schirmeister |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm900946n |