Spectra for:
Alexander Breuning, Björn Degel, Franziska Schulz, Christian Büchold, Martin Stempka, Uwe Machon, Saskia Heppner, Christoph Gelhaus, Matthias Leippe, Matthias Leyh, Caroline Kisker, Jennifer Rath, August Stich, Jiri Gut, Philip J. Rosenthal, Carsten Schmuck, Tanja Schirmeister
Compound 4 4-AMINO-2-(TERT.-BUTOXYCARBONYLAMINO)-4-OXOBUTYL_ETHYL-FUMARATE
Compound 5 (S)-5-AMINO-2-(TERT.-BUTOXYCARBONYLAMINO)-5-OXOPENTYLT_ETHYL_FUMARATE
Compound 6 (S)-4-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-2-PHENYLACETAMIDO)-4-OXOBUTYL_ETHYL_FUMARATE
Compound 7 (S)-5-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-2-PHENYLACETAMIDO)-5-OXOBUTYL_ETHYL_FUMARATE
Compound 8 (S,E)-ETHYL_4-(4-AMINO-1-TERT.-BUTOXY-1,4-DIOXOBUTYN-2-YLAMINO)-4-OXOBUT-2-ENOATE
Compound 9 (E)-3-[(S)-1-METHOXYCARBONYL-2-(TRITYL-CARBAMOYL)-ETHYLCARBOMOYL]-ACRYLIC_ACID_ETHYLESTER
![(E)-3-[(S)-1-METHOXYCARBONYL-2-(TRITYL-CARBAMOYL)-ETHYLCARBOMOYL]-ACRYLIC_ACID_ETHYLESTER](/api/compound/4suXx1fBsTG.png?h=300&w=458 "(E)-3-[(S)-1-METHOXYCARBONYL-2-(TRITYL-CARBAMOYL)-ETHYLCARBOMOYL]-ACRYLIC_ACID_ETHYLESTER")
Compound 10 (S,E)-TERT.-BUTYL-5-AMINO-2-(4-ETHOXY-4-OXOBUT-2-ENAMIDO)-5-OXOPENTANOATE
Compound 11 (S,E)-METHYL_2-(4-ETHOXY-4-OXOBUT-2-ENAMIDO)-5-OXO-5-(TRITYLAMINO)-PENTANOATE
Compound 12 (S,E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLIC_ACID_ETHYLESTER
Compound 13 (E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLIC_ACID
Compound 14 (S)-2-[(E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYL-ETHYLCARBAMOYL)-ACRYLOYL-AMINO]-3-PHENYLPROPIONIC_ACID_BENYLESTER
![(S)-2-[(E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYL-ETHYLCARBAMOYL)-ACRYLOYL-AMINO]-3-PHENYLPROPIONIC_ACID_BENYLESTER](/api/compound/9jjQrYQVwSt.png?h=300&w=458 "(S)-2-[(E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYL-ETHYLCARBAMOYL)-ACRYLOYL-AMINO]-3-PHENYLPROPIONIC_ACID_BENYLESTER")
Compound 16A (S,E)-ETHYL-4-((S/R)-2-(TERT.-BUTOXYCARBONYLAMINO)-2-PHENYLACETAMIDO)-7-OXO-7-(TRITYLAMINO)-HEPT-2-ENOATE;MAJOR_ISOMER
Compound 17 (S,E)-ETHYL_4-(4-AMINO-1-TERT.-BUTOXYCARBONYL-1,4-DIOXOBUTAN-2-YLAMINO)-BUT-2-ENOATE
Compound 18 (S,E)-TERT.-BUTYL_5-AMINO-2-(4-ETHOXY-4-OXOBUT-2-ENYLAMINO)-5-OXOPENTANOATE
Compound 19 (S,E)-ETHYL-4-(1-BENZYLOXYCARBONYL-2-PHENYLETHYLAMINO)-BUT-2-ENOATE
Compound 20 (2-S,5-S,8-S,11-S,E)-1-BENZYL_16-ETHYL_11-(3-AMINO-3-OXOPROPYL)-8-CYCLOHEXYL-5-ISOPROPYL-2-METHYL-4,7,10-TRIOXO-3,6,9,12-TETRAAZAHEXADEC-14-ENE-1,
Compound 21 (S,E)-ETHYL-3-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-4-CARBAMOYL-BUTOXY]-ACRYLATE
![(S,E)-ETHYL-3-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-4-CARBAMOYL-BUTOXY]-ACRYLATE](/api/compound/DUjNJcQngXi.png?h=300&w=458 "(S,E)-ETHYL-3-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-4-CARBAMOYL-BUTOXY]-ACRYLATE")
Compound 22 (Z)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;CIS-ISOMER
![(Z)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;CIS-ISOMER](/api/compound/51oV5qwlm83.png?h=300&w=458 "(Z)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;CIS-ISOMER")
Compound 22 (E)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;TRANS_ISOMER
![(E)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;TRANS_ISOMER](/api/compound/4rsPcySj59g.png?h=300&w=458 "(E)-ETHYL-3-[(S)-1-(TERT.-BUTOXYCARBONYL)-2-CARBAMOYLETHYL-AMINO]-ACRYLATE;TRANS_ISOMER")
Compound 23 (S)-4-TERT.-BUTYL_5-AMINO-2-(3-ETHOXY-3-OXOPROP-1-ENYLAMINO)-5-OXOPENTANOATE;CIS_ISOMER
Compound 23 (S)-4-TERT.-BUTYL_5-AMINO-2-(3-ETHOXY-3-OXOPROP-1-ENYLAMINO)-5-OXOPENTANOATE;TRANS_ISOMER
Compound 24 (S,E)-ETHYL_4-(4-AMINO-2-(TERT.-BUTOXYCARBONYLAMINO)-4-OXOBUTAMOYLOXY)-BUT-2-ENOATE
Compound 25 (S,E)-4-ETHOXY-4-OXOBUT-2-ENYL_5-AMINO-2-(TERT.-BUTOXYCARBONYLAMINO)-5-OXOPENTANOATE
Compound 26 (E)-ETHYL-4-((S)-4-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-4-METHYLPENTANAMIDO)-4-OXOBUTANOYLOXY)-BUT-2-ENOATE
Compound 27 (E)-ETHYL_4-((S)-4-AMINO-2-((S)-(TERT.-BUTOXYCARBONYLAMINO)-2-CYCLOHEXYLACETAMIDO)-4-OXOBUTANOYLOXY)-BUT-2-ENOATE
Compound 28 (S)-((E)-4-ETHOXY-4-OXOBUT-2-ENYL)-5-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-4-METHYLPENTANAMIDO)-5-OXOPENTANOATE
Compound 29 (S)-((E)-4-ETHOXY-4-OXOBUT-2-ENYL)-5-AMINO-2-((S)-2-(TERT.-BUTOXYCARBONYLAMINO)-2-CYCLOHEXYLACETAMIDO)-5-OXOPENTANOATE
Compound 30 (6-S,9-S,12-S)-((E)-4-ETHOXY-4-OXOBUT-2-ENYL)_12-(3-AMINO-3-OXOPROPYL)-9-ISOBUTYL-2,2,6-TRIMETHYL-4,7,10-TRIOXO-3-OXA-5,8,11-TRIAZATRIDECAN-13-OAT
Compound 31 (2-S,5-S,8-S,11-S,E)-1-AMIDE_16-HYDROXY-11-(3-AMINO-3-OXOPROPYL)-8-(2-METHYLPROPYL)-5-ISOPROPYL-2-ISOPROPYL-4,7,10,13-TETRAOXO-3,6,9,12-TETRAAZAHE
Compound 32 (S,E)-BENZYL-2-(BUT-2-ENOYLAMINO)-3-PHENYLPROPIONATE
Compound 33 (S,E)-ETHYL_5-(2-BENZYLOXYCARBONYLAMINO-3-PHENYLPROPIONYLOXY)-PENT-2-ENOATE
Compound 34 (Z)-BUT-2-ENDIOIC_ACID-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-3-PHENYLPROPYLESTER]-ETHYLESTER
![(Z)-BUT-2-ENDIOIC_ACID-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-3-PHENYLPROPYLESTER]-ETHYLESTER](/api/compound/EbC6fX0gwAH.png?h=300&w=458 "(Z)-BUT-2-ENDIOIC_ACID-[(S)-2-TERT.-BUTOXYCARBONYLAMINO-3-PHENYLPROPYLESTER]-ETHYLESTER")
Compound 35 (S)-2-((Z)-3-ETHOXYCARBONYL-ACRYLOYLAMINO)-4-(TRITYL-CARBAMOYL)-BUTYRIC_ACID_METHYLESTER
Compound 37 (Z)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLIC_ACID
Compound 39 (Z)-3-[(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLIC_ACID
![(Z)-3-[(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLIC_ACID](/api/compound/BIiIMds0o6z.png?h=300&w=458 "(Z)-3-[(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLIC_ACID")
Compound 41 (S)-BENZYL-2-{(S)-2-[(S)-2-((Z)-3-CARBOXY-ACRYLOYLAMINO)-3-PEHNYLPROPIONYLAMINO]-PROPIONYLAMINO}-4-METHYLPENTANOATE
![(S)-BENZYL-2-{(S)-2-[(S)-2-((Z)-3-CARBOXY-ACRYLOYLAMINO)-3-PEHNYLPROPIONYLAMINO]-PROPIONYLAMINO}-4-METHYLPENTANOATE](/api/compound/JSluiaJVlu7.png?h=300&w=458 "(S)-BENZYL-2-{(S)-2-[(S)-2-((Z)-3-CARBOXY-ACRYLOYLAMINO)-3-PEHNYLPROPIONYLAMINO]-PROPIONYLAMINO}-4-METHYLPENTANOATE")
Compound 42 (S)-BENZYL-2-[(Z)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLOYL-AINO]-3-PHENYLPROPIONATE
![(S)-BENZYL-2-[(Z)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLOYL-AINO]-3-PHENYLPROPIONATE](/api/compound/CmNgmRfKz2U.png?h=300&w=458 "(S)-BENZYL-2-[(Z)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLOYL-AINO]-3-PHENYLPROPIONATE")
Compound 43 (S)-BENZYL-2-{/Z)-3-(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLOYLAMINO}-3-PHENYLPROPIONATE
![(S)-BENZYL-2-{/Z)-3-(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLOYLAMINO}-3-PHENYLPROPIONATE](/api/compound/6vtufbthwPd.png?h=300&w=458 "(S)-BENZYL-2-{/Z)-3-(S)-1-((S)-1-BENZYLOXYCARBONYLETHYLCARBAMOYL)-2-PHENYLETHYLCARBAMOYL]-ACRYLOYLAMINO}-3-PHENYLPROPIONATE")
Compound 44 (S,Z)-ETHYL-4-TERT.-BUTOXYCARBONYLAMINO-5-PEHNYLPENT-2-ENOATE
Compound 45 (S,Z)-ETHYL-4-(2-TERT.-BUTOXYCARBONYLAMINO-3-PHENYLPROPIONYLAMINO)-BUT-2-ENOATE
(E)-3-((S)-1-BENZYLOXYCARBONYL-2-PHENYLETHYLCARBAMOYL)-ACRYLIC_ACID_TERT.-BUTYLESTER
(Z)-ETHYL-4-TERT.-BUTOXYCARBONYLAMINOBUT-2-ENOATE
Citation
| Citation | J.MED.CHEM.,53,1951(2010) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 5 |
| Volume | 53 |
| Page(s) | 1951-1963 |
| Year | 2010 |
| Author(s) | Alexander Breuning, Björn Degel, Franziska Schulz, Christian Büchold, Martin Stempka, Uwe Machon, Saskia Heppner, Christoph Gelhaus, Matthias Leippe, Matthias Leyh, Caroline Kisker, Jennifer Rath, August Stich, Jiri Gut, Philip J. Rosenthal, Carsten Schmuck, Tanja Schirmeister |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm900946n |