Spectra for:
Esther Lobatón, Fátima Rodríguez-Barrios, Federico Gago, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez
Compound 8 [1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-CHLORO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-CHLORO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/4qYnU6VoFXN.png?h=300&w=458 "[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-CHLORO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
Compound 9 [1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-BROMO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-BROMO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/JsFsBSDCeFB.png?h=300&w=458 "[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-BROMO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
Compound 10 [1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/5UupBJpQRA6.png?h=300&w=458 "[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
Compound 12 [1-[2'-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![[1-[2'-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/1RGmSlxEWPC.png?h=300&w=458 "[1-[2'-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
Compound 15C [1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-VINYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-VINYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/wAmLgBsCvY.png?h=300&w=458 "[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-VINYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
Compound 15E [1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-PHENYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-PHENYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/8y9bCCVCyOv.png?h=300&w=458 "[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-PHENYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
#11;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![#11;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/GkNwGXxfida.png?h=300&w=458 "#11;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-IODO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
#15A;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(2-METHOXYACRYLOYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![#15A;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(2-METHOXYACRYLOYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/J9qGFsSlpbT.png?h=300&w=458 "#15A;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(2-METHOXYACRYLOYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
#15D;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-(E)-(1-HYDROXY-2-PROPENYLENO)-1'',2''-OXATHIOLE-2'',2''-DIO
![#15D;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-(E)-(1-HYDROXY-2-PROPENYLENO)-1'',2''-OXATHIOLE-2'',2''-DIO](/api/compound/H9s3oNWCEX6.png?h=300&w=458 "#15D;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-(E)-(1-HYDROXY-2-PROPENYLENO)-1'',2''-OXATHIOLE-2'',2''-DIO")
#17A;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(2-METHOXYACRYLOYL)-1'',2''-OXATHIOLE-2''
![#17A;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(2-METHOXYACRYLOYL)-1'',2''-OXATHIOLE-2''](/api/compound/FcBHRrUNZLF.png?h=300&w=458 "#17A;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(2-METHOXYACRYLOYL)-1'',2''-OXATHIOLE-2''")
#17D;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(1-HYDROXY-2-PROPENYLENO)-1'',2''-OXATHI
![#17D;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(1-HYDROXY-2-PROPENYLENO)-1'',2''-OXATHI](/api/compound/2nJFwkLw5Ml.png?h=300&w=458 "#17D;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(E)-(1-HYDROXY-2-PROPENYLENO)-1'',2''-OXATHI")
#17E;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-PHENYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)
![#17E;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-PHENYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)](/api/compound/DFGjEahEBFr.png?h=300&w=458 "#17E;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-(4''-AMINO-3''-PHENYL-1'',2''-OXATHIOLE-2'',2''-DIOXIDE)")
#17F;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(2-THIENYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE]
![#17F;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(2-THIENYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE]](/api/compound/FbhaEAgRmTC.png?h=300&w=458 "#17F;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(2-THIENYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE]")
#17G;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(1-PROPYNYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE
![#17G;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(1-PROPYNYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE](/api/compound/Cb3wbfGoczg.png?h=300&w=458 "#17G;[1-[2',5'-BIS-O-(TERT.-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3-N-(METHYL)-THYMINE]-3'-SPIRO-5''-[4''-AMINO-3''-(1-PROPYNYL)-1'',2''-OXATHIOLE-2'',2''-DIOXIDE")
Citation
| Citation | J.MED.CHEM.,45,3934(2002) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 18 |
| Volume | 45 |
| Page(s) | 3934-3945 |
| Year | 2002 |
| Author(s) | Esther Lobatón, Fátima Rodríguez-Barrios, Federico Gago, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm020820h |