Spectra for:
Tim H. M. Jonckers, Sabine van Miert, Kanyanga Cimanga, Christian Bailly, Pierre Colson, Marie-Claire De Pauw-Gillet, Hilde van den Heuvel, Magda Claeys, Filip Lemière, Eddy L. Esmans, Jef Rozenski, Ludo Quirijnen, Louis Maes, Roger Dommisse, Guy L. F. Lemière, Arnold Vlietinck, Luc Pieters
Compound 1 N 9-CYANO-2-TRIFLUOROMETHYL-NEOCRYPTOLEPINE
Compound 1A Neocryptolepine
Compound 1B 2-METHOXY-NEOCRYPTOLEPINE
Compound 1C 2-BROMO-NEOCRYPTOLEPINE
Compound 1D 2-CHLORO-NEOCRYPTOLEPINE
Compound 1E 2-FLUORO-NEOCRYPTOLEPINE
Compound 1F 2-IODO-NEOCRYPTOLEPINE
Compound 1G 2-METHYL-NEOCRYPTOLEPINE
Compound 1H 2-NITRO-NEOCRYPTOLEPINE
Compound 1I 2-METHYLTHIO-NEOCRYPTOLEPINE
Compound 1J 2-CYANO-NEOCRYPTOLEPINE
Compound 1K 9-CYANO-NEOCRYPTOLEPINE
Compound 1L 2-CHLORO-9-CYANO-NEOCRYPTOLEPINE
Compound 1M 9-CYANO-2-METHOXY-NEOCRYPTOLEPINE
Compound 1O 9-CYANO-2-FLUORO-NEOCRYPTOLEPINE
Compound 1R 1-METHYOXY-NEOCRYPTOLEPINE
Compound 1S 1-BROMO-NEOCRYPTOLEPINE
Compound 1U 1-TRIFLUOROMETHYL-NEOCRYPTOLEPINE
Compound 1V 3-METHOXY-NEOCRYPTOLEPINE
Compound 1W 3-BROMO-NEOCRYPTOLEPINE
Compound 1X 3-CHLORO-NEOCRYPTOLEPINE
Compound 1Y 3-TRIFLUOROMETHYL-NEOCRYPTOLEPINE
Compound 2' 4-Amino-3-iodobenzonitrile
Compound 3 2-(2-Trimethylsilylethynyl)aniline
Compound 3' 4-AMINO-3-(2-TRIMETHYLSILYLETHYNYL)-BENZENECARBONITRILE
Compound 5' 3-(2-TRIMETHYLSILYLETHYNYL)-4-TRIPHENYLPHOSPHORANYLIDENE-AMINO-BENZENECARBONITRILE
Compound 5A N-PHENYL-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-PHENYL-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/GbDTl8lpgXy.png?h=300&w=458 "N-PHENYL-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5B N-(4-METHOXYPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-METHOXYPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/1MP1mR0atud.png?h=300&w=458 "N-(4-METHOXYPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5C N-(4-BROMOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-BROMOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/yA4NrXDUS8.png?h=300&w=458 "N-(4-BROMOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5D N-(4-CHLOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-CHLOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/9mH2I3r8Zmg.png?h=300&w=458 "N-(4-CHLOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5E N-(4-FLUOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-FLUOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/2bsPMKiFnlP.png?h=300&w=458 "N-(4-FLUOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5F N-(4-IODOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-IODOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/HCuY8Xeqsg9.png?h=300&w=458 "N-(4-IODOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5G N-(4-METHYLPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-METHYLPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/CnqHhcqheN2.png?h=300&w=458 "N-(4-METHYLPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5H N-(4-NITROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-NITROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/xtJ1g7VW2R.png?h=300&w=458 "N-(4-NITROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5I N-(4-METHYLTHIOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-METHYLTHIOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/BY95IsLH44M.png?h=300&w=458 "N-(4-METHYLTHIOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5J N-(4-CYANOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(4-CYANOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/KirUpRIc204.png?h=300&w=458 "N-(4-CYANOPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5P N-(1-NAPHTHYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(1-NAPHTHYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/6CGAqsPgtsk.png?h=300&w=458 "N-(1-NAPHTHYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 5Q N-(2,4-DICHLOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA
![N-(2,4-DICHLOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA](/api/compound/CP6F40AkzHO.png?h=300&w=458 "N-(2,4-DICHLOROPHENYL)-N'-[2-(2-TRIMETHYLSILYLETHYNYL)-PHENYL]-THIOUREA")
Compound 8A 11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/AMhSVK6ShR0.png?h=300&w=458 "11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8B 2-METHOXY-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-METHOXY-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/8ahY5DsvyL7.png?h=300&w=458 "2-METHOXY-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8C 2-BROMO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-BROMO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/JmKO72f15vR.png?h=300&w=458 "2-BROMO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8D 2-CHLORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-CHLORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/8hBdS9pmdK0.png?h=300&w=458 "2-CHLORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8E 2-FLUORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-FLUORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/580YNfrXbjq.png?h=300&w=458 "2-FLUORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8F 2-IODO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-IODO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/CjtEYrjSJ7S.png?h=300&w=458 "2-IODO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8G 2-METHYL-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-METHYL-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/KFL2iAevvG9.png?h=300&w=458 "2-METHYL-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8H 2-NITRO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-NITRO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/C1Lyhj1eP7V.png?h=300&w=458 "2-NITRO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8I 2-METHYLTHIO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-METHYLTHIO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/CXYRQaCH8Il.png?h=300&w=458 "2-METHYLTHIO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8J 2-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/E2RaQBtR7JA.png?h=300&w=458 "2-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8K 9-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![9-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/GR1y8x4f4HO.png?h=300&w=458 "9-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8L 2-CHLORO-9-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2-CHLORO-9-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/j7a85Xym8t.png?h=300&w=458 "2-CHLORO-9-CYANO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8M 9-CYANO-2-METHOXY-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![9-CYANO-2-METHOXY-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/CnopkNhJSNA.png?h=300&w=458 "9-CYANO-2-METHOXY-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8N 9-CYANO-2-TRIFLUOROMETHYL-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![9-CYANO-2-TRIFLUOROMETHYL-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/E0Kqq22nwFl.png?h=300&w=458 "9-CYANO-2-TRIFLUOROMETHYL-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8O 9-CYANO-2-FLUORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![9-CYANO-2-FLUORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/KBi4rCjXh74.png?h=300&w=458 "9-CYANO-2-FLUORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 8P 7-TRIMETHYLSILYL-NAPHTHO-[1,2-B]-ALPHA-CARBOLINE
![7-TRIMETHYLSILYL-NAPHTHO-[1,2-B]-ALPHA-CARBOLINE](/api/compound/FZhHU7ZOamb.png?h=300&w=458 "7-TRIMETHYLSILYL-NAPHTHO-[1,2-B]-ALPHA-CARBOLINE")
Compound 8Q 2,4-DICHLORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE
![2,4-DICHLORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/4PGYteuv8Kd.png?h=300&w=458 "2,4-DICHLORO-11-TRIMETHYLSILYL-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 9 C 2-BROMO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9 H 2-NITRO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9 J 2-CYANO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9 K 9-CYANO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9A 11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9B 2-METHOXY-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9D 2-CHLORO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9E 2-FLUORO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9F 2-IODO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9G 2-METHYL-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9I 2-METHYLTHIO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9L 2-CHLORO-9-CYANO-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 9M 9-CYANO-2-METHOXY-11-TRIMETHYLSILYL-NEOCRYPTOLEPINE
Compound 10 Q 2,4-DICHLORO-6H-INDOLO-[2,3-B]-QUINOLINE
![2,4-DICHLORO-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/Dgf6Dqel0zK.png?h=300&w=458 "2,4-DICHLORO-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 10B 2-METHOXY-6H-INDOLO-[2,3-B]-QUINOLINE
![2-METHOXY-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/JJ9wbuP8zPF.png?h=300&w=458 "2-METHOXY-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 10D 2-CHLORO-6H-INDOLO-[2,3-B]-QUINOLINE
![2-CHLORO-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/ESUnjHJISH1.png?h=300&w=458 "2-CHLORO-6H-INDOLO-[2,3-B]-QUINOLINE")
Compound 10E 2-FLUORO-6H-INDOLO-[2,3-B]-QUINOLINE
![2-FLUORO-6H-INDOLO-[2,3-B]-QUINOLINE](/api/compound/9lL1P0KfOUz.png?h=300&w=458 "2-FLUORO-6H-INDOLO-[2,3-B]-QUINOLINE")
Citation
| Citation | J.MED.CHEM.,45,3497(2002) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 16 |
| Volume | 45 |
| Page(s) | 3497-3508 |
| Year | 2002 |
| Author(s) | Tim H. M. Jonckers, Sabine van Miert, Kanyanga Cimanga, Christian Bailly, Pierre Colson, Marie-Claire De Pauw-Gillet, Hilde van den Heuvel, Magda Claeys, Filip Lemière, Eddy L. Esmans, Jef Rozenski, Ludo Quirijnen, Louis Maes, Roger Dommisse, Guy L. F. Lemière, Arnold Vlietinck, Luc Pieters |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm011102i |