Spectra for:
Antonín Holý, Ivan Votruba, Milena Masojídková, Graciela Andrei, Robert Snoeck, Lieve Naesens, Erik De Clercq, Jan Balzarini
Compound 13B 4-AMINO-1-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDIN-6(1H)-ONE
![4-AMINO-1-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDIN-6(1H)-ONE](/api/compound/2QVAwLgIalg.png?h=300&w=458 "4-AMINO-1-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDIN-6(1H)-ONE")
Compound 14A 4-AMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE
![4-AMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/2PZfDV3w4Jl.png?h=300&w=458 "4-AMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 14B 4-AMINO-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE
![4-AMINO-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/ICITi9jAnwv.png?h=300&w=458 "4-AMINO-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 16A 2,4-DIAMINO-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE
![2,4-DIAMINO-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE](/api/compound/26pGjntXdVx.png?h=300&w=458 "2,4-DIAMINO-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE")
Compound 16B 2,4-DIAMINO-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE
![2,4-DIAMINO-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE](/api/compound/GkTbEoGXDmg.png?h=300&w=458 "2,4-DIAMINO-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE")
Compound 17A 2,4-DIAMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE
![2,4-DIAMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/5CMDTxYnk1i.png?h=300&w=458 "2,4-DIAMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 17B 2,4-DIAMINO-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE
![2,4-DIAMINO-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/7GkqGtTAKsa.png?h=300&w=458 "2,4-DIAMINO-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 19A 2-AMINO-4-METHYL-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE
![2-AMINO-4-METHYL-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE](/api/compound/KwUZiADRRZo.png?h=300&w=458 "2-AMINO-4-METHYL-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE")
Compound 19B 2-AMINO-4-METHYL-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE
![2-AMINO-4-METHYL-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE](/api/compound/BJYVvKYrHKy.png?h=300&w=458 "2-AMINO-4-METHYL-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE")
Compound 20A 2-AMINO-4-METHYL-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE
![2-AMINO-4-METHYL-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/3bWTlygcwql.png?h=300&w=458 "2-AMINO-4-METHYL-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 20B 2-AMINO-4-METHYL-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE
![2-AMINO-4-METHYL-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/65rVjiJyJ3d.png?h=300&w=458 "2-AMINO-4-METHYL-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 23B 2-AMINO-4-CYCLOPROPYLAMINO-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE
![2-AMINO-4-CYCLOPROPYLAMINO-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE](/api/compound/8HwNIzeKa3D.png?h=300&w=458 "2-AMINO-4-CYCLOPROPYLAMINO-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE")
Compound 26B 2-AMINO-4-(DIMETHYLAMINO)-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE
![2-AMINO-4-(DIMETHYLAMINO)-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE](/api/compound/FHfdWT5v3Mi.png?h=300&w=458 "2-AMINO-4-(DIMETHYLAMINO)-1-[2-(PHOSPHONOMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE")
Compound 27B 2-AMINO-4-(DIMETHYLAMINO)-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE
![2-AMINO-4-(DIMETHYLAMINO)-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/Itc7JT4NPW8.png?h=300&w=458 "2-AMINO-4-(DIMETHYLAMINO)-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 28 2-AMINO-4-CHLORO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE
![2-AMINO-4-CHLORO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/GAozjAMmkqf.png?h=300&w=458 "2-AMINO-4-CHLORO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 29A 2-AMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-4-HYDROXYPYRIMIDINE
![2-AMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-4-HYDROXYPYRIMIDINE](/api/compound/3DkIwumpWNb.png?h=300&w=458 "2-AMINO-6-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHOXY]-4-HYDROXYPYRIMIDINE")
Compound 29B 2-AMINO-4-HYDROXY-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE
![2-AMINO-4-HYDROXY-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/1kHVCov6j2Q.png?h=300&w=458 "2-AMINO-4-HYDROXY-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 30 2-AMINO-4-CHLORO-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE
![2-AMINO-4-CHLORO-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE](/api/compound/D0wI0hmxu12.png?h=300&w=458 "2-AMINO-4-CHLORO-1-[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-PYRIMIDIN-6(1H)-ONE")
Compound 32B 2-AMINO-4,6-BIS-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE
![2-AMINO-4,6-BIS-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/9TjU33FEigW.png?h=300&w=458 "2-AMINO-4,6-BIS-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE")
Compound 36A 4-AMINO-6-HYDROXY-2-[[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-SULFANYL]-PYRIMIDINE
![4-AMINO-6-HYDROXY-2-[[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-SULFANYL]-PYRIMIDINE](/api/compound/2fu7Q15P9Lm.png?h=300&w=458 "4-AMINO-6-HYDROXY-2-[[2-(DIISOPROPYLPHOSPHORYLMETHOXY)-ETHYL]-SULFANYL]-PYRIMIDINE")
Compound 38B 2,4-DIAMINO-6-(R)-[2-(PHOSPHONOMETHOXY)-PROPOXY]-PYRIMIDINE
![2,4-DIAMINO-6-(R)-[2-(PHOSPHONOMETHOXY)-PROPOXY]-PYRIMIDINE](/api/compound/8ifRLuSjMG4.png?h=300&w=458 "2,4-DIAMINO-6-(R)-[2-(PHOSPHONOMETHOXY)-PROPOXY]-PYRIMIDINE")
Compound 38B 2,4-DIAMINO-6-(S)-[2-(PHOSPHONOMETHOXY)-PROPOXY]-PYRIMIDINE
![2,4-DIAMINO-6-(S)-[2-(PHOSPHONOMETHOXY)-PROPOXY]-PYRIMIDINE](/api/compound/CmZATIm5RrY.png?h=300&w=458 "2,4-DIAMINO-6-(S)-[2-(PHOSPHONOMETHOXY)-PROPOXY]-PYRIMIDINE")
Compound 41B 4-AMINO-2-METHYLSULFANYL-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE
![4-AMINO-2-METHYLSULFANYL-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE](/api/compound/2D3eYl3ODEm.png?h=300&w=458 "4-AMINO-2-METHYLSULFANYL-6-[2-(PHOSPHONOMETHOXY)-ETHOXY]-PYRIMIDINE")
Citation
| Citation | J.MED.CHEM.,45,1918(2002) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 9 |
| Volume | 45 |
| Page(s) | 1918-1929 |
| Year | 2002 |
| Author(s) | Antonín Holý, Ivan Votruba, Milena Masojídková, Graciela Andrei, Robert Snoeck, Lieve Naesens, Erik De Clercq, Jan Balzarini |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm011095y |