Spectra for:
José M. Bartolomé-Nebreda, M. Teresa García-López, Rosario González-Muñiz, Edurne Cenarruzabeitia, Miriam Latorre, Joaquín Del Río, Rosario Herranz
Compound 3 (4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/7atCgP4dqLh.png?h=300&w=458 "(4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 4 (4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/F9HTZ3t9CHZ.png?h=300&w=458 "(4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 5A (4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/D4FLmzkueXw.png?h=300&w=458 "(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 5B (4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/HqcKuFIFfi3.png?h=300&w=458 "(4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXO-1-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 6A (4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/INbOC2XUj9H.png?h=300&w=458 "(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 6B (4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/GmPGiTc54SC.png?h=300&w=458 "(4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-OXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 7 (4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/A9TsA13DfBy.png?h=300&w=458 "(4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 8A (4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/3FP7E6RLb6f.png?h=300&w=458 "(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 8B (4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/9muxq5pGcty.png?h=300&w=458 "(4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DITHIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 9A (4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/JnlBv7D16et.png?h=300&w=458 "(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 11 (4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/Fs8Oo6bcvLE.png?h=300&w=458 "(4A-R*,5-S*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 12A (4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/1eQxayoqJUb.png?h=300&w=458 "(4A-S*,5-R*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 12B (4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/5utAC0bTL9G.png?h=300&w=458 "(4A-R*,5-S*)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-3-THIOXOPERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 13A (4A-S,5-R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(4A-S,5-R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/FbamDMSSQb2.png?h=300&w=458 "(4A-S,5-R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1-OXO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 14A (3-R,4A-S,5-R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-METHOXY-1-OXO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE
![(3-R,4A-S,5-R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-METHOXY-1-OXO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE](/api/compound/KQCwSCi9KuI.png?h=300&w=458 "(3-R,4A-S,5-R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-3-METHOXY-1-OXO-PERHYDROPYRIDO-[1,2-C]-PYRIMIDINE")
Compound 22A,B (4A-R*,5-R*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE
![(4A-R*,5-R*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE](/api/compound/2tznyHqxK26.png?h=300&w=458 "(4A-R*,5-R*)-2-BENZYL-5-(TERT.-BUTOXYCARBONYL)-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE")
Compound 23A/24B (R,S)/(S,R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE
![(R,S)/(S,R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE](/api/compound/H6UVoaIgTfX.png?h=300&w=458 "(R,S)/(S,R)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE")
Compound 23C/24D (R,R)/(S,S)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE
![(R,R)/(S,S)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE](/api/compound/D1vvJD0lkyA.png?h=300&w=458 "(R,R)/(S,S)-2-BENZYL-5-[N-(TERT.-BUTOXYCARBONYL)-L-TRYPTOPHYL]-AMINO-1,3-DIOXO-PERHYDROPYRROLO-[1,2-C]-PYRIMIDINE")
Citation
| Citation | J.MED.CHEM.,44,4196(2001) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 24 |
| Volume | 44 |
| Page(s) | 4196-4206 |
| Year | 2001 |
| Author(s) | José M. Bartolomé-Nebreda, M. Teresa García-López, Rosario González-Muñiz, Edurne Cenarruzabeitia, Miriam Latorre, Joaquín Del Río, Rosario Herranz |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm010898i |