Spectra for:
Stephen J. Gregson, Philip W. Howard, John A. Hartley, Natalie A. Brooks, Lesley J. Adams, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston
Compound 5 1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-(11A-S)-7-METHOXY-2-METHYLIDENE-1,2,3,11A-TETRAHYDRO-5H-PYRROLO-[2,1-C]-[1,4]-BENZODIAZEPIN-5-ONE];IMINE-FORM
![1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-(11A-S)-7-METHOXY-2-METHYLIDENE-1,2,3,11A-TETRAHYDRO-5H-PYRROLO-[2,1-C]-[1,4]-BENZODIAZEPIN-5-ONE];IMINE-FORM](/api/compound/2jRqH1sObht.png?h=300&w=458 "1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-(11A-S)-7-METHOXY-2-METHYLIDENE-1,2,3,11A-TETRAHYDRO-5H-PYRROLO-[2,1-C]-[1,4]-BENZODIAZEPIN-5-ONE];IMINE-FORM")
Compound 9 (2S,4R)-N-(Allyloxycarbonyl)-4-hydroxy-2-(hydroxymethyl)pyrrolidine
Compound 10 (2-S,4-R)-N-(ALLYLOXYCARBONYL)-2-(TERT.-BUTYLDIMETHYLSILYLOXYMETHYL)-4-HYDROXY-PYRROLIDINE
Compound 11 (2-S)-N-(ALLYLOXYCARBONYL)-2-(TERT.-BUTYLDIMETHYLSILYLOXYMETHYL)-4-OXOPYRROLIDINE
Compound 12 (2-S)-N-(ALLYLOXYCARBONYL)-2-(TERT.-BUTYLDIMETHYLSILYLOXYMETHYL)-4-METHYLIDENEPYRROLIDINE
Compound 13 (2S)-2-(tert-Butyldimethylsilyloxymethyl)-4-methylidenepyrrolidine
Compound 17 (2-S)-1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(2-AMINO-5-METHOXY-1,4-PHENYLENE)-CARBONYL]]-BIS-[2-(HYDROXYMETHYL)-4-METHYLIDENEPYRROLIDINE]
![(2-S)-1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(2-AMINO-5-METHOXY-1,4-PHENYLENE)-CARBONYL]]-BIS-[2-(HYDROXYMETHYL)-4-METHYLIDENEPYRROLIDINE]](/api/compound/2jXy8WTTYug.png?h=300&w=458 "(2-S)-1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(2-AMINO-5-METHOXY-1,4-PHENYLENE)-CARBONYL]]-BIS-[2-(HYDROXYMETHYL)-4-METHYLIDENEPYRROLIDINE]")
Compound 21 1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-(11A-S)-7-METHOXY-2-METHYLIDENE-1,2,3,10,11,11A-HEXAHYDRO-5H-PYRROLO-[2,1-C]-[1,4]-BENZODIAZEPIN-5,11-DIONE]
![1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-(11A-S)-7-METHOXY-2-METHYLIDENE-1,2,3,10,11,11A-HEXAHYDRO-5H-PYRROLO-[2,1-C]-[1,4]-BENZODIAZEPIN-5,11-DIONE]](/api/compound/FLh4nSVTfRD.png?h=300&w=458 "1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-(11A-S)-7-METHOXY-2-METHYLIDENE-1,2,3,10,11,11A-HEXAHYDRO-5H-PYRROLO-[2,1-C]-[1,4]-BENZODIAZEPIN-5,11-DIONE]")
#18;(2-S)-1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(2-ALLYLOXYCARBONYLAMINO-5-METHOXY-1,4-PHENYLENE)-CARBONYL]]-BIS-[2-(HYDROXYMETHYL)-4-METHYLIDENEPYRROLIDINE]
![#18;(2-S)-1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(2-ALLYLOXYCARBONYLAMINO-5-METHOXY-1,4-PHENYLENE)-CARBONYL]]-BIS-[2-(HYDROXYMETHYL)-4-METHYLIDENEPYRROLIDINE]](/api/compound/ETAhKxqn0LA.png?h=300&w=458 "#18;(2-S)-1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(2-ALLYLOXYCARBONYLAMINO-5-METHOXY-1,4-PHENYLENE)-CARBONYL]]-BIS-[2-(HYDROXYMETHYL)-4-METHYLIDENEPYRROLIDINE]")
#19;1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(11S,11A-S)-10-(ALLYLOXYCARBONYL)-11-HYDROXY-7-METHOXY-2-METHYLIDENE-1,2,3,10,11,11A-HEXAHYDRO-5H-PYRROLO-[2,1-C]-[1,
![#19;1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(11S,11A-S)-10-(ALLYLOXYCARBONYL)-11-HYDROXY-7-METHOXY-2-METHYLIDENE-1,2,3,10,11,11A-HEXAHYDRO-5H-PYRROLO-[2,1-C]-[1,](/api/compound/K4wWrXiPLi4.png?h=300&w=458 "#19;1,1'-[[(PROPANE-1,3-DIYL)-DIOXY]-BIS-[(11S,11A-S)-10-(ALLYLOXYCARBONYL)-11-HYDROXY-7-METHOXY-2-METHYLIDENE-1,2,3,10,11,11A-HEXAHYDRO-5H-PYRROLO-[2,1-C]-[1,")
Citation
| Citation | J.MED.CHEM.,44,737(2001) |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Issue | 5 |
| Volume | 44 |
| Page(s) | 737-748 |
| Year | 2001 |
| Author(s) | Stephen J. Gregson, Philip W. Howard, John A. Hartley, Natalie A. Brooks, Lesley J. Adams, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston |
| Publisher | American Chemical Society (ACS) |
| DOI | 10.1021/jm001064n |