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EZETIMIBE;(3-R,4-S)-1-(4-FLUOROMETHYL)-3[(S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)-AZETRIDIN-2-ONE

Compound with spectra: 5 NMR

EZETIMIBE;(3-R,4-S)-1-(4-FLUOROMETHYL)-3[(S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)-AZETRIDIN-2-ONE
SpectraBase Compound ID CIQZFJGp47i
InChI InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
InChIKey OLNTVTPDXPETLC-XPWALMASSA-N
Mol Weight 409.43 g/mol
Molecular Formula C24H21F2NO3
Exact Mass 409.14895 g/mol
Enantiomer InChIKey OLNTVTPDXPETLC-ZRBLBEILSA-N

View Spectrum of EZETIMIBE;(3-R,4-S)-1-(4-FLUOROMETHYL)-3[(S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)-AZETRIDIN-2-ONE

19F NMR Spectrum
Copyright Copyright © 2016-2024 W. Robien, Inst. of Org. Chem., Univ. of Vienna. All Rights Reserved.
Solvent HET

View Spectrum of EZETIMIBE;(3-R,4-S)-1-(4-FLUOROMETHYL)-3[(S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)-AZETRIDIN-2-ONE

19F NMR Spectrum
Copyright Copyright © 2016-2024 W. Robien, Inst. of Org. Chem., Univ. of Vienna. All Rights Reserved.
Solvent HET

View Spectrum of EZETIMIBE;(3-R,4-S)-1-(4-FLUOROMETHYL)-3[(S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)-AZETRIDIN-2-ONE

13C NMR Spectrum
Copyright Copyright © 2016-2024 W. Robien, Inst. of Org. Chem., Univ. of Vienna. All Rights Reserved.
Solvent DMSO-D6

View Spectrum of EZETIMIBE;(3-R,4-S)-1-(4-FLUOROMETHYL)-3[(S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)-AZETRIDIN-2-ONE

13C NMR Spectrum
Copyright Copyright © 2016-2024 W. Robien, Inst. of Org. Chem., Univ. of Vienna. All Rights Reserved.
Solvent CDCl3+DROPS_OF-DMSO-D6

View Spectrum of EZETIMIBE;(3-R,4-S)-1-(4-FLUOROMETHYL)-3[(S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)-AZETRIDIN-2-ONE

13C NMR Spectrum
Copyright Copyright © 2016-2024 W. Robien, Inst. of Org. Chem., Univ. of Vienna. All Rights Reserved.
Solvent DMSO-D6
  • EZETIMIBE;1-(4-FLUOROPHENYL)-3-(R)-[3-(4-FLUOROPHENYL)-3-(S)-HYDROXYPROPYL]-4-(S)-(4-HYDROXYPHENYL)-2-AZETIDINONE
EZETIMIBE;EZE;1-(4-FLUOROPHENYL)-3-(R)-[3-(4-FLUOROPHENYL)-3-(S)-HYDROXYPROPYL]-4-(S)-(4-HYDROXYPHENYL)-2-AZETIDINONE
Ethyl 4-(4-methoxyphenyl)-2-oxo-1-phenyl-1-azacyclobutane-3-carboxylate
Ethyl 1-(4-methoxyphenyl)-2-oxo-4-phenyl-1-azacyclobutane-3-carboxylate
3,4-trans-N-(Carbobenzyloxy)-3-amino-4-phenylazetidin-2-one
1,4-DIPHENYL-3-(p-METHOXYPHENYL)-2-AZETIDINONE
3-(p-CHLOROPHENYL)-1,4-DIPHENYL-2-AZETIDINONE
cis-3-Chloro-1-(p-methoxyphenyl)-4-o-tolyl-2-azetidinone
trans-3-Chloro-1-(p-methoxyphenyl)-4-o-tolyl-2-azetidinone
DL-1,3-bis(p-chlorophenyl)-4,5-diphenyl-2-imidazolidinone
DL-4,5-diphenyl-1,3-di-p-tolyl-2-imidazolidinone
Title Journal or Book Year
Structure of the major degradant of ezetimibe Journal of Pharmaceutical and Biomedical Analysis 2012
Structural elucidation of a process-related impurity in ezetimibe by LC/MS/MS and NMR Journal of Pharmaceutical and Biomedical Analysis 2010
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